Zantac is prescribed for treatment and prevention of ulcers in the stomach and intestines, it works decreasing amount of acid in the stomach.
Common use Zantac is a blocker of H2-histamine receptors. The mechanism of action consists in the blockade of histamine H2-receptors of parietal cells in gastric mucous layer. This medication suppresses day and night secretion of HCl (both basal and stimulated), reduces the amount of gastric juices caused by stretching of the stomach with food load and by the action of hormones and biogenic stimulants such as gastrin, histamine, acetylcholine, pentagastrin, caffeine. Zantac reduces the amount of HCl in gastric juice almost without suppressing "liver" enzymes associated with cytochrome P450. It does not affect the concentration of gastrin in plasma, production of mucus. Zantac reduces pepsin activity. This medication is use to treat and prevent stomach and duodenal ulcers, gastrointestinal disorders caused by NSAID, heartburn, hypersecretion of gastric juice, symptomatic ulcers, ulcers caused by stress, erosive esophagitis, reflux esophagitis, Zollinger-Ellison syndrome and other conditions.
Dosage and direction Take it orally with or without food. Correction of the dose should be made in patients with significantly abnormal liver or kidney function. Besides tablets this medication maybe administered intramuscularly (IM) or intravenously.
Missed dose If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to compensate a missed dose by taking an extra one.
Overdose If you suspect that you took too much of the medication seek for immediate medical attention. Symptoms of overdose include lack of coordination, feeling light-headed, or fainting.
Storage Save Zantac in a dry place away from sunlight at room temperature between 15-30 C (59-86 F).
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