Cytoxan is used for treatment of cancer with cytotoxic effect.
Common use Cytoxan belongs to the drugs for treatment of cancer with cytotoxic effect. Its active substance cyclophosphamide is converted in the liver by cytochrome P450 into two active substances acrolein and phosphoramide. They are the active compounds, and they slow the growth of cancer cells inhibiting their proliferation and metabolism. First of all this effect concerns cells of uncontrolled growing but also damages other cells of the body resulting in serious side effects. Cytoxan also can be referred to as immunosuppressive agent. Cytoxan is used to treat malignant lymphoma (lymphocytic and gistiotsitarnaya lymphoma, lymphogranulomatosis, Burkitt lymphoma, lymphoma, mixed type), multiple myeloma, leukemias (lymphocytic leukemia, granulocytic leukemia, myelocytic leukemia, acute lymphoblastic leukemia in children), neuroblastoma, ovarian adenocarcinoma, retinoblastoma, breast carcinoma.
Dosage and direction For adults and children Cytoxan is administered intravenously by 40-50 mg/kg over 3-5 days in divided doses. An oral dose of this medication is oral dose is 1-5 mg/kg daily. Dosage should be corrected on a basis of regular blood tests for white blood cell count. This medication can be taken orally also with or without food.
Missed dose If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.
Overdose Symptoms of Cytoxan overdose are not expected. If you suppose that took too much of it call your doctor immediately.
Storage Store at room temperature between 20-25 C (68-77 F). Keep out of heat, moisture, sunlight, of the reach of children. Storage in a bathroom is not recommended.
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