Premarin is is a mixture of estrogen hormones used to treat menopause symptoms such as hot flashes, vaginal dryness, irritation and dryness, to prevent osteoporosis in postmenopausal women.
Common use Premarin is a mixture of estrogen hormones which regulates development and functions of female reproductive system, formation of female secondary sex characteristics. On entering into the bloodstream it forms a complex with a specific receptor (in the fallopian tubes, cervix, excretory ducts of the mammary glands, vagina, urethra, breast, liver, hypothalamus, hypophisis), stimulates synthesis of DNA and proteins. It results in proliferation of the epithelium, increased sensitivity of the uterus and tubes muscles of to medications stimulatign their motility. This medication decreases bone resorption of Ca2 + in menopause, prevents involution of the genitals. Premarin is used to treat symptoms of menopause which include hot flashes, vaginal dryness, vaginal irritation and dryness, to prevent osteoporosis in postmenopausal women. Replacement therapy in peri- and postmenopausal women, ovarian hypofunction (primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea) and other conditions.
Dosage and direction Take this medication once daily as prescribed with a full glass of water with or without food. Premarin may be administered for a cyclic treatment which consists of 25 days on followed by 5 days. Do not take in larger amounts than prescribed. Individual dosage depends on your condition (for hypogonadism 0.3 mg or 0.625 mg daily, for preventing postmenopausal osteoporosis is 0.3 mg/day). Try your best to take it regularly to get the best benefit from it. Do not take with grapefruit juice, it increases levels of estrogen.
Missed dose Take the missed dose as soon as you remember about it. If it is almost time of your next dose just skip it and return to your regular schedule.
Overdose Immediate medical attention in needed in case you overdosed intake of the medicine. Symptoms may include vomiting, nausea, and vaginal bleeding.
Storage Premarin should be stored at room temperature, between 15-30 C (59-86 F). The right temperature to store the injection is between 2-8 C (36-46 F).
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